Meet the “BIG FIVE”

List of TCAs

This is the full list of TCAs.

The TCAs include the following agents which are predominantly serotonin and/or norepinephrine reuptake inhibitors:

• Amitriptyline (Tryptomer, Elavil)
• Amitriptylinoxide (Amioxid, Ambivalon, Equilibrin)
• Butriptyline (Evadyne)
• Clomipramine (Anafranil)
• Demexiptiline (Deparon, Tinoran)
• Desipramine (Norpramin, Pertofrane)
• Dibenzepin (Noveril, Victoril)
• Dimetacrine (Istonil, Istonyl, Miroistonil)
• Dosulepin/Dothiepin (Prothiaden)
• Doxepin (Adapin, Sinequan)
• Imipramine (Tofranil, Janimine, Praminil)
• Imipraminoxide (Imiprex, Elepsin)
• Lofepramine (Lomont, Gamanil)
• Melitracen (Deanxit, Dixeran, Melixeran, Trausabun)
• Metapramine (Timaxel)
• Nitroxazepine (Sintamil)
• Nortriptyline (Pamelor, Aventyl, Norpress)
• Noxiptiline (Agedal, Elronon, Nogedal)
• Pipofezine (Azafen/Azaphen)
• Propizepine (Depressin, Vagran)
• Protriptyline (Vivactil)
• Quinupramine (Kevopril, Kinupril, Adeprim, Quinuprine)

and

• Amineptine (Survector, Maneon, Directim) – Norepinephrine-dopamine reuptake inhibitor
• Iprindole (Prondol, Galatur, Tetran) – 5-HT₂ receptor antagonist
• Opipramol (Insidon, Pramolan, Ensidon, Oprimol) – σ receptor agonist
• Tianeptine (Stablon, Coaxil, Tatinol) – Selective serotonin reuptake enhancer
• Trimipramine (Surmontil) – 5-HT₂ receptor antagonist

Read more: http://www.answers.com/topic/tricyclic-antidepressant#ixzz325jhptRX

 

BUT…only five of the commonly used TCA will be discussed. Thus the term “Big Five” is used.

The Big Five of the TCAs:

1. Amitriptyline

2. Desipramine

3. Imipramine

4. Nortriptyline

5. Doxepin

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