Tricyclics Antidepressants

Watch this introductory video about TCAs 🙂 Credits to the owner.


Points to Ponder

depression by yellowcaseartist-d29h0e7

“You must make a decision that you are going to move on. It won’t happen automatically. You will have to rise up and say, “I don’t care how hard this is, I don’t care how disappointed I am, I’m not going to let this get the best of me. I’m moving on with my life”

-Joel Osteen, Your Best Life Now: 7 Steps to Living at Your Full Potential

Disappointments? Failures? Rejections? Feeling pressure? Sadness? Feeling outcast?

Yes, these are these are some of the reasons or emotions why our beautiful life comes into darkness.Giving your efforts into fullest then you will realize in the end your effort is not sufficient at all. BUT these rejections and failures would not be the reasons to make us stop to reach our dreams and makes our parents proud. we should learned that no matter what happen, how much darkness you will feel in your heart there will always  be light after those trials. just hang on to God because He will not leave you and put your trust in yourself because believing in you means believing to Him.

-The Authors.


TCA and Depression First Before Anything Else

This educational blog talks about tricyclic antidepressant drugs or TCA. TCA are antidepressants, so they are use for treating depression. They are known as the earliest antidepressants gaining popularity in the 1950’s.

The BIG FIVE are the five common TCA drugs namely: Amitryptiline, Nortryptiline, Desipramine, Imipramine and Doxepin. These drugs are generic named.

Several tests or assays are used to determine the levels of TCA in the human body. Toxic concentration or the high dosage of these drugs can be fatal causing hallucination and suicidal attempts. The heart of this educational blog will be these tests mentioned.


This educational blog is also publish for a requirement under Clinical Chemistry 3: Toxicology subject.


Depression is common affecting about 121 million people in the world. The Philippines, once considered as one of the HAPPIEST nations worldwide has the highest number of depression cases in Southeast Asia (WHO, 2010).

It is important to understand that when someone has depression there are actual physical changes in the structure of the brain as well as reduced levels of important chemicals called “NEUROTRANSMITTERS”. These are important for mood regulation.


To know more about the tests use in determining TCA levels, browse the pages. ☺


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